Genetically engineered virus kills cancer

Paris(nie) A genetically engineered virus test in 30 in critical condition liver cancer patients for long periods significantly their lives, killing tumors and inhibition of the growth of new, scientists said on Sunday.Sixteen patients survived a high dose of the treatment for an average of 14.1 months, compared with 6.7 months for Lal 14 who received a low dose."For the first time in medical history and we have shown that a genetically engineered virus that can improve the survival of cancer patients," said study co-author David Kern and Agence France-Presse.
Trial for four weeks with a vaccine Pexa-594 JX or more, which was published in the journal Nature Medicine, promise for the treatment of advanced solid tumors."Despite the progress in cancer treatment over the past 30 years with chemotherapy and biological weapons, the majority of solid tumors remain incurable once they metastatic (spread to other organs)," the authors wrote.Noted that there is a need to develop "more active immune strength."Pexa-more "aims to double later and destroy the cancer cells at the same time make the patients themselves immune defense system attack cancer cells, too," Kern said of the California-based company biotherapy Jennerex."The results showed that the treatment Pexa-more in each of the doses resulting in a reduction of tumor size and decreased blood flow to tumors," said a statement Jennerex.
"The data show that more than Pexa-induced therapy more immune response against the tumor."
Has been designed Pexa-more of the vaccinia virus used as a vaccine for decades, including the eradication of smallpox.The trial showed Pexa-more well-tolerated in both high and low doses, with flu-like symptoms continue for a day or two in all patients and severe nausea and vomiting in one.
The authors said the largest trial has to confirm the results. A follow-up phase with about 120 patients are currently being.Pexa-being tested more in other types of tumors.